US stock - ACTC.OB, now changed to OCAT (Ocata Therapeutics)

IpohMan69

Two words, buy more, for those that follow this and have skin in the game.

The odds that this turns into real jackpot is much better than the 550 million powerball jackpot if you have enough shares....LOL

http://finance.yahoo.com/news/ac ... sage-133000398.html

http://www.equities.com/news/hea ... &cat=industrial

IpohMan69

I sent a reply to a friend of mine who is hard hit by SuperStorm Sandy here in New York City, to tell her hang in there as she is also invested in ACT. I was also asking her permission to post a picture of her car floated. Her funny reply is below as quoted, good to see that her spirit is still high:

You sure can post my car grows four legs when the sea water rush in and climb on top of my fence for safety. LOL..
You did so much home work on ACTC. If it blow you deserve it and I just simply got lucky to know you. Best luck for both of us again
Sent from my iPad

This is the picture of her car in front of her house after the storm. Her house first floor and basement were flooded and totally destroyed. She has to spend a lot of money to fix it and buy a new car too.



And my e-mail to her earlier, was below :

Grace,

Hang in there....I am pretty sure next year is the show time for ACTC and early investors. In the beginning we already expect the trials to go for about 36 months. Now we are already half way thru and so far no safety issues and also showing efficacy. Again, from the biological view point, because these are cell base therapies, if it works for one, it will work for many. Unlike drug base, where there is long guessing game/monitoring of efficacy and also have to monitor side effects, simple cell therapy of ACT does not have that kind of complications. It is, for cells in the eye, either works or die off, especially these terminally differentiated RPE cells. Unlike those that try to inject cell to the spinal cord where they have no way of monitoring where they actually go visually. You also know that for RPE cell injection procedure, it is fast and easy, 15 minutes out-patient procedure and most retinal specialists/surgeons already know how to do this; thus minimal training will be needed. Essentially, this is an easy, fast, off-the shelf out-patient procedure that is aiming at the huge un-met medical needs of AMD and SMD. That is why I am so bullish on ACT because it is on track and showing now at least 10 cases of confirm safety and varies degree of efficacies, with 16 patients injected; across 4 sites, 2 different trials and two countries(US and UK). That is also why the ACT management labelled it as "low hanging fruits" from the beginning even before the FDA IND approval. Thus if ACT trials can't make it big, I will lost all confidence in medical science advancements for the future.

Best of luck,

IpohMan69

If you look at the pps every day, it is pretty scary isn't it? Welcome to the roller-coaster.  This stock will sure test your guts to the extreme.....

Below I am just directly quoted a post from iCell forum, I totally agreed with it. Just FYI, do the judgment yourself whether you agree or not.

*********************************************************************

The idea that ACTC as an investment is an all or nothing type of investment is
only partially correct!

It was correct more than 2 years ago prior to the approval of ACTC's First IND Trials.
Its chances of success went doubled with the approval in Europe.
And, its risk profile have improved continuously over the last year.

Please note that the FDA is not dumb.
Nor Europe.
These agencies will not waste their resources.
Dr. Schwartz, Dr. Bainbridge, and the top 4 of the top 5 Hospital/Clinics are not dumb.
All of these guys have reputations to keep, patients to care for, and MONEY to Make.

And, on the Finance Side... You think the investors of 35 million dollars in Chicago
are dumb?

I am posting this thread... for long investors.
The idea that ACTC is an All or Nothing deal... is preposterously wrong!

The best gauge of risk relative to ACTC is the discount rate given by the 35 million dollar purchase agreement in Chicago. And it was a very good rate which immediately tells you that the probability of success is on ACTC's side.

Our long investor's greatest risk now is PATIENCE and your susceptibility to be swayed by the negative posts at ICell. This is your risk.

My own very personal view... is that there is no way ACTC will get to nothing.
And here is a bold position... All of it is before ACTC to Win.
No other Stem Cell company has this potential!

IpohMan69

If you guys and gals wonder what is going on with the little spike today, here is why.

The whole article is copy and pasted here, as many of us, including me, do not have account to log on to WSJ.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Stem-Cell Trial Without Embryo Destruction

By JONATHAN D. ROCKOFF

A Massachusetts biotechnology company said it expects as early as Friday to start the process for regulatory approval of what experts said would be the first human trial involving stem cells created by reprogramming adult cells back to an embryonic-like state.

Researchers have been experimenting with treatments derived from stem cells, which can grow into other cell types or tissues. But such cells are typically obtained by destroying human embryos, a controversial practice. Scientists are experimenting with other types of stem cells derived from bone marrow or umbilical cord blood, but such cells are limited in the types of cells they can grow into.

The newer approach involves reprogramming mature cells, typically from the skin, without the need to destroy embryos. Two of the researchers who developed the process shared a Nobel Prize this year for the work.

Advanced Cell Technology Inc. ACTC 0.00%of Marlborough, Mass., says it wants to test blood-clotting particles, called platelets, made from such reprogrammed cells. People with certain forms of leukemia, anemia and other conditions need repeat infusions of platelets to avoid bleeding to death, but can develop resistance to the donated cells over time, making them less effective, experts say. Stem-cell derived platelets could overcome that problem because they could be derived from a patient's own cells.

"This would really be a dramatic advance in medicine, but it remains to be seen if this would be successful," said Alan Michelson, a platelet researcher at Harvard Medical School and Boston Children's Hospital who would lead a clinical trial in the U.S. studying ACT's stem-cell derived platelets.

ACT has proposals for clinical trials and says testing could begin as early as the end of next year if regulators sign off. The U.S. Food and Drug Administration declined to comment, saying federal rules prevent it from discussing any therapies that may be under development.

Robert Lanza, ACT's chief scientific officer, said that the company has the "capacity to make enough" platelets for the initial clinical trials but would "take time to scale up for widespread use."

"It doesn't require any embryos. It doesn't require eggs. It doesn't require any destruction of embryos," Dr. Lanza said.

Among the challenges facing laboratories and firms that have been racing to make so-called induced-pluripotent-stem-cell treatments is making enough of the cells. Another is preventing genetic abnormalities to some cells that could cause tumors.

Platelets don't carry the risk of genetic defects because they don't have DNA, experts say. Yet a risk remains that some stray cells with DNA could contaminate a batch of the stem-cell derived platelets, according to James Thomson, one of the researchers who first turned human skin cells into pluripotent stem cells in 2007.

"You have to manipulate the cells quite a bit, so I think you'll have to overcome the safety concerns of the FDA and other regulatory bodies," said Dr. Thomson, of the Morgridge Institute for Research in Madison, Wis.

Dr. Lanza said ACT takes "multiple measures" to prevent contamination of its supply, and platelets can be irradiated before use.

ACT's idea for the U.S. trial would be to infuse both normal platelets and stem-cell-derived platelets into eight patients, Dr. Lanza said, and compare how the cells function. A separate set of eight patients would receive normal platelets and platelets derived from human embryonic stem cells.

Each of the cells would be tagged with a chemical allowing researchers to track their presence in study subjects. Researchers would periodically draw blood from study subjects and then analyze the blood to see if the tagged stem-cell-derived platelets are surviving and circulating like normal platelets.

If the stem-cell derived platelets worked like normal platelets, "the potential impact would be great," said Cynthia Dunbar, a stem-cell researcher at the National Heart, Lung and Blood Institute and editor of the journal Blood.

http://online.wsj.com/article/SB ... 4666.html#printMode

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Also, below is a blog from one of the scientists in the field.

http://www.ipscell.com/2012/12/a ... lets-some-thoughts/

IpohMan69

Happy New Year to everyone, may you and your beloved family have a healthy and prosperous year of 2013.

Here are some news about ACTC, nothing to concerns about and still on track to make it as a big winner for me as an investor, although of course the pps does not reflect any of it NOW.....LOL.

1)No reverse split. As to me, either way would not matters for me as long term investor.

http://www.advancedcell.com/news ... rse-split/index.asp

2)ACT is featured in magazine "New Scientist"

http://finance.yahoo.com/news/sc ... uced-133000152.html

http://www.newscientist.com/arti ... tem-cell-trial.html

http://www.newscientist.com/special/smart-guide-2013

3)Paul Kneopfler, a stemcell scientist that is not associated with ACT and have been actively following the development of the field, blogged this. Pay attention to his #3 predictions about ACT.

http://www.ipscell.com/2012/12/m ... edictions-for-2013/

4)Another reason that I am bullish on ACT, is about the pipeline for blood platelets, is taking shapes slowly. If  you think RPE potential is huge, this is even bigger than RPE. Of course, ACT has to transform itself from development to bed side treatment with the "low hanging fruits" RPE program first to gain wall street confident.

http://www.grc.org/programs.aspx?year=2013&program=megakar

https://www.ipscell.com/2012/12/ ... lets-some-thoughts/

http://www.fiercebiotech.com/sto ... -therapy/2012-12-14

The WSJ article itself is already posted on the previous post #124.

IpohMan69

You better believe that every indication shows that the ACTC storm is in brewing and will be coming SOON...LOL.

http://www.theatlantic.com/healt ... -stem-cell/266574/#

In below video, pay attention to the market potential of just 1%.

http://www.youtube.com/watch?v=i-v1beWV3l4

http://www.nature.com/news/new-year-new-science-1.12122

IpohMan69

For those of you that have stake in this, enjoy the news and the ride! I am expecting a good price appreciation within a year. So far since the beginning of this year, it is up 60% +  from around .055. I am still under water but I am not worry at all and expect the pps to raise steadily in 2013.

http://www.bloomberg.com/news/20 ... rejects-appeal.html

http://www.forbes.com/sites/john ... stem-cell-research/

This latest news below is the final confirmation that I needed to make the call that "The jackpot prize is in the bag with this investment" because this confirmed that engraftment of cell in Dry AMD patiients, which is the one with the 90% of market for all AMD patients. Now to me this is scientifically proven, just need to follow through the FDA trials to produce mass data point and wait for the big day of either buyout or JV news to pop up. In short, this trials is "100% Safety, No Side effects, visual acuity lasting 18+ months, no current therapy, landmark results...", this is unseen in FDA history.

http://finance.yahoo.com/news/ad ... ical-133000279.html

IpohMan69

This is the evident that now the trials focus will be shifted from safety to efficacy.

http://finance.yahoo.com/news/pa ... -act-133000914.html

Again, no safety issue is pretty much unheard of in FDA trials history. Because with chemical drug module development, there are always some side effects seen and eventually FDA has to weight in side effect risks versus percentages of effectiveness when they approve the drug for market.

Also, ACT settled an important litigation. This is very important to many shareholders that owning this stock because we feared that this might bring massive dilution. It turned out that it is settled in a much less damage to the current shareholders, some in cash and some in shares. In the grand scheme of future revenue potentials this is being viewed as minor because we believe that this company will worth billions in market cap. Of course, this is just an educated guess for many shareholders. It is still waiting to be proven and that is why this is still a PENNY stock. If it is proven, it will not be penny anymore. There are still two more litigations left. One is SEC, that is expected to be settled by paying about 3 millions to SEC. And last one is with a company called Aronson/Gorton, which ACT felt strongly that they can win the case thus still in progress. We should know the outcome some times in April.

http://finance.yahoo.com/news/ad ... ment-213000157.html

manhattan913

I invested in this stock too. I bought in for .07 shares...Do you think this stock will be 爆槓 in the end of 2013?
How many shares you bought in now? lol

IpohMan69

manhattan913 发表于 11-3-2013 02:47 AM
I invested in this stock too. I bought in for .07 shares...Do you think this stock will be 爆槓 in t ...

You are very very lucky that you enter at .07. If I am at this price point, I would have accumulated about 2 millions shares...LOL. Oh well, I have no regret at all and still very happy that I am in deep "shxt" with this. I am drinking some strong coffee today thus just feel bold to do something crazy, yet again...LOL.

I am seeing a steady readership of my post even though I have not really updated much about it lately, thus I am sure there are folks that have the same question like you : how much really this guy, talking about great great potentials in this company, invested in it but not just talking.....

Again, do your DD/research, invest only what you can afford to lose. Never just invest by only someone said so and you did not follow with your own research to verify the information.

Edit, picture removed, people seen enough!!! LOL

manhattan913

IpohMan69 发表于 11-3-2013 10:48 PM
You are very very lucky that you enter at .07. If I am at this price point, I would have accumulat ...

You invested USD $$$$$$ already...now is half cut.   You still look so calm. If i were you I couldn't sleep for afew nights.

I have extra money left so I only bought in 50000 shares already. . . .  I think i will bought in another 50000shares lol...that will be my limit.

How much higher you think this stock will climb ?  I know you mentioned it before it could be $ 10 or more. Lol you made me smile when I read that post.


I just read your posts here  as a research of my own..lol I think this medicine will work out. So I invested   although it is not 100% guarantee ...let fate leads the way

IpohMan69

Members in icell forum predicted that there are four JVs possible. This years, based on the management released information about BOD will tied their bonus to signing of JV, we predicted with educated guess that between now and end of year, there will be at least one JV signed. This JV will mostlikely not the RPE's AMD or SMD market. But rather the platelets program with quasi-government entity

Go search and read the transcripts of last week quarterly conference call. It packed a lot of information.

If they can in fact sign one JV, which we think any one of the 4 JV; will be in the billions number, this will push the pps over 50 cents initially. Because they will have cash infusion of 100x of millions  + milestone payments. After that the wall street main stream will all the sudden notice this unknown giant and it will just be history from there.

My own personal expectation is not long after the signing of the JV, like within 6 months, this will be over $3, which is my number to start taking profits. The high end is "sky is the limit"  . If they can break the first JV, this is done deal and everyone will want this company stock as it's technologies of not just RPE, MSC, platelets, MMD will all be recognized as time goes by.

I will sell off 20% of my holdings after it reaches over $3 and the rest of the 80% will be long term holdings for the next 5 to 15 years. Of course I will monitor the company direction closely.

manhattan913

Where can i find those transcripts?  There are 4 JV, if at least can sign one JV it will be over $3 and your personal prediction this will happen within 6 months? If One JV is signed this actc will become wanted for Wall street guys is that what you're trying to say? This information is too much for me lol....
What if they signed 3 JVs in the end of 2013, what will happene? I am curious about it, Can you tell me your educated guess? lol
This shxt is getting excited day by day.....

IpohMan69

You misunderstood my sentence of "My own personal expectation is not long after the signing of the JV, like within 6 months, this will be over $3, which is my number to start taking profits."   What I meant is 6 months after the JV signed, not that I fully expect the next six months ( March to September this year) there will be a JV sign. It is after the JV signed, where the pps will start going upward, from there; I will expect the pps could be over $3.

I do expect, from now to the end of the year of 2013, a JV is completed.

manhattan913

I see your point...end of the year.
Members in icell forum?? another forum about this stock? Can you forward to me?

IpohMan69

Here is the link to the transcripts, the last one on the thread is the 3/7 call.

http://investorstemcell.com/foru ... echnology/27965.htm

If you spend time ( a lot of time) to read the inside out of these links, you will understand the risks and potentials of this company like I do.

http://investorstemcell.com/forum/advanced-cell-technology/

http://investorstemcell.com/foru ... -palace-premium.htm

IpohMan69

Gary is a panelist alongside representatives from Roche, Park BioVentures, and CIRM. Nice to see our CEO on the big worldwide stage...!  Why do they invite this little company to the world stage?.....LOL.....hope you get the hint.     

http://www.partnering360.com/insight/showroom/id/368

http://www.ebdgroup.com/bes/index.php

IpohMan69

Another step closer.

http://finance.yahoo.com/news/ac ... sage-123000247.html

IpohMan69

http://www.spiegel.de/internatio ... cells-a-892475.html

IpohMan69

I don't think I ever posted this video, event was held around October last year.

http://www.youtube.com/watch?v=oYINCgpsC0k