US stock - ACTC.OB, now changed to OCAT (Ocata Therapeutics)

IpohMan69

The power of internet; and credited to a non-chinese iCell member who digged this out.

http://www.yatai.com/html/news_12_7180_1.html

http://investorstemcell.com/foru ... ses-media/12016.htm

If you listened to the ACT company shareholders conference call in early November 2011 or read the transcripts after that; Gary said that he just came back from China where he visited a few companies and talking to potential partners; here is the evident.

Nachogy

Thanks Ipohman to introduce this to us. I had invest some of my money into it.

You can't lost much if you buy, but you will win big if it happen.

This is definately one that worth to try.

IpohMan69

Nachogy, I am sure at the moment you are happy to have invested because I am guessing that your base is around 10 cents but again this is for the long term. If you really wanted to play it safe, sell enough to recoup your cost and the let the left over free share ride the waves for the long term. Although I have to say for me, I would not sell.

IpohMan69

This gives you some insights about why the pps is being going up lately. Read the latest blog and digest the information. There is a chance, it might or might not happen that, the pps will go down a little bit again when the proxy passed where about 380 millions share will be given to the bondholders after Jan 24. The effect will essentially depending how the markets take it along with some anticipated news outlined in this blog; and if the bondholders hold the shares or dump the share out in big chunk.

http://www.thechairmansblog.com/gary-rabin/
The blog itself pretty much confirmed that we have good results from the first two patients. How "good" is the results; whether is a home run or grand slam, we have to wait till when it is published.

Nachogy

Ipohman, I will put this as a long term investment since it has a big potential right now.

For the blog, it will boost up the stock market but it is not neccessary always the truth. As the owner need more people to invest in their company, sometime they will tell you whatever you like to hear.

That had happen few years ago when I bought Isilon stock. Isilon constantly giving false information that they are getting big contract with Sony but it ended up that it was a false statement.

Anyway, I think Isilon is no longer in the stock market right now.

Just to be careful and constantly follow up with the news.

IpohMan69

Nachogy,

I understand you point and where you are coming from. Don't worry, you can bet that I am putting this company under my telescope every day as I have big financial interests and medical interests in it. The made or break of this company will not be the management, it is the science like I said along. If the science works, everything else will fall into places even if the management is inept, then the company will most likely get bought over because their Intellectual Properties still worth billions.

Rest assure also that with the involvement of Dr. Schwartz from UCLA in the discussion panel where he openly gone on record saying that he has zero financial interests in ACT, this speaks volume because folks like Dr. Schwartz care for the advancement of therapy to cure diseases and to treat illness effectively.

IpohMan69

This is a very good article to know about the history of ACT.

http://www.nature.com/news/stem- ... ever-say-die-1.9759

IpohMan69

Another validation that the trial is safe to go on further.

Folks, you have to understand this: this is not the conventional trials with drugs, this is trial with live cells. These are differentiated RPE cells. If they are safe, they will start working/healing.  When they are placed in the right area where they are suppose to be injected, mother nature will make them do what they are good at; in this case rescue photoreceptors in the eyes, halting progressive eye sight lost; might also have the protential to improve some visual acuity. Halting the progressive lost itself is already a home run. If if also proved that some restore of visual acuity, that would be a grand slam. That is why the up and coming peer-reviewed publication is going to be huge if that is what transpired.

If you place the RPE cells that supposed to go into the eyes but instead to spinal cord, then it might not be safe because these cell do not know what to do and might form tumors. But in the right place, they are programmed by nature to do their magic. This is already proved in animal studies.

http://finance.yahoo.com/news/Le ... -653807741.html?x=0http://finance.yahoo.com/news/Leading-Eye-Institute-bw-653807741.html?x=0

IpohMan69

What a good news to start the New Year.

http://www.nytimes.com/2012/01/2 ... artner=yahoofinance

http://www.cnn.com/video/?hpt=he ... ll-breakthrough.cnn

http://www.npr.org/blogs/health/ ... tudy?ps=sh_stcathdl

I am not worry about the incoming dilution at all, things will be falling into places and now waiting for one day the joint venture or buy out news!!!

Wish you all Happy Chinese New Year, be strong, healthy and prosperity.

Nachogy

oh yea, there was a spike at around 12pm - 1pm shortly after the news come out.

Thanks Ipohman, this stock has help me to make extra income in just few weeks.

I do not know about the rest of you, but it really has a great potential to get more higher in short future.

IpohMan69

For those that are interested, here give you links to many news outlet about the preliminary result.

http://investorstemcell.com/foru ... ses-media/12929.htm

For the coming weeks, mostlikely the pps will be zigzagging due to the passing of proxy to authorize 1 billion shares(92% of the shareholders voted for). Within Jan 25th to Feb 7(10 business days) about 300 millions will be giving to bondholders, causing dilution to the current shareholders. But all indications show that ACTC is now a time bomb for either be bought out or doing JV with big pharma company!!! Be patience if you are in this!!!  Again, use your own judgement and do your homework!

ivan2k

IpohMan69
的确 是个人才 谢谢你提供资讯  
太多了 要慢慢 的读

IpohMan69

回复 72# ivan2k

谢谢你的赞美，我实际上不是人才。

我只是把公开的资料整理以后报告和论述给大家。 当然也加上我本人的判断. That is why you need to do your DD and make your own judgement.

http://www.marketwatch.com/story/act-announces-third-patient-with-stargardts-disease-treated-in-us-clinical-trial-with-rpe-cells-derived-from-embryonic-stem-cells-2012-02-13?reflink=MW_news_stmp

Up until now the stock is till unnoticed by the world, which to me is a good thing becuase every month I am adding 10K share. To me, I am not worry about the general public. People are worried about if this therapy will pass the FDA trials all the way and get approved to go commercialize, which will be at least 2 years away. But I am not because what I am betting is this company will be bought out or doing joint venture partnering way before that, where of course should make it spike up easily. Like I said before, the big pharma companies will not just sit there without bidding for it as they have insider information about the technical result details and at the same times ACT will not have enough money and man power to get this to commercialize by their own.

http://www.marketwatch.com/story/act-announces-third-patient-with-stargardts-disease-treated-in-us-clinical-trial-with-rpe-cells-derived-from-embryonic-stem-cells-2012-02-13?reflink=MW_news_stmp

This is the third patient injected in US, and on Jan 23, the first in Europe (in England) is also injected with the highly differentiated RPE cells.
The science is already proven by the Lancet paper. All the company needs is just prove that more and more positive results with zero safety issues to show the naysayers. Of course, if there is some safety issues, this will be the big breaker for ACT. ACT folks know it and they will try to do their best to control this by making sure the RPE cells are fully differentiated from hESC before they are injected into the eyes. Long terms wise still unknown but atleast now more than 6 months since the first two patients of July 12 2011, they are still safe and effective.

http://www.wakefieldexpress.co.uk/news/local/wakefield-news/stem_cells_could_bring_back_vision_for_a_wakefield_business_owner_1_4211602

Again, patients(to be treated) and patience are what we need in this stock.

ivan2k

我诚心的 感恩 你,可以体会到你的用心
不过这只股在10年前最高涨的哦9.00 usd
先在才0.10,但是我会注意这项 股
太多资料 我要慢慢读 , 另方面我英文不好 所以会读的较慢
您要是 有另方 的股票 资讯 ,也请你提供 提供!
祝 你 情人节快乐 哈哈

Nachogy

Ipohman, thanks for your updates.

I had noticed that some are talking about using their roth to buy stock. I wonder if you are doing the same or if you know how to do this?

I search on google and one response showing that this has to be pre-set when we open an account with broker. However, I had already have the accounts with brokers and don't really feel like open another one.

Would you mind to please shed some light to me?

IpohMan69

回复 75# Nachogy

Nachogy,

I will address ROTH in PM to you, as this needs some explanations to you and it does not concern people that are not US resident or US citizen.

IpohMan69

Two days ago one of my friends that I keep in the loop about ACT send me this e-mail.

Grace gkXXXX@verizon.net
Feb 14 (1 day ago)

See where you from now, case in point is either work for another 20 years or retire in few years. Hari hari makan angin!  Good game plan.
Do you have any say on all  this political controversies and ethical issue about destruction of human embryos?

And below is my response to her.

I am not worry, either politically or ethnically. That is because :

1)ACT has a patented technology of extracting a single cell from embryo without destroying it, named as "Blastomere technology". To my understanding, in the Blastocyst stage, ACT extracts a single cell and the embryo is not destroyed.

http://en.wikipedia.org/wiki/Blastocyst

http://www.advancedcell.com/our-technology/selected-publications/

"In February of this year(2011) ACT was issued a patent on its blastomere technique: Patent Number 7,893,315 broadly covers the technology"

Currently the cells used in these current FDA clinical injections(sponsored by  ACT) can not claim this because they were from embryos that was destroyed while ACT team was experimenting and trying to perfecting this patented technique many years ago. In the future, cell lines will be derived from stem cell of embryo without destroying the embryo.

2)In IVF procedures for many couples that cannot conceive naturally, they usually created multiple embryos to maximize the chances of pregnancy. All it takes is only one out of the many. Thus those left over will either be discarded(destroyed) medically or if they are not discarded, they will be frozen. These embryos cannot survive nor develop into babies outside of a female womb. Most of the couples choose to destroy them or donate them for medical research. The arguments of babies killer is a bit absurd for me as when they are an embryo, technically they are cell mass and cannot survive without a womb, which is a big different than killing a fully developed baby from embryo inside the womb.

3)Politicians now are mostly unclear about their support of the issue or go against the issue but that would not matter when the clinical trials and scientific data do show that there is great value for using stem cells from embryo to cure diseases. When ACT is going further along the trial and prove that it is working and the risk is small ( let say one out of 50 developed tumor, of course I made this up now), go tell millions of the family that you go against this as a politician and see what the members of the families that directly affected by this would say. The advancement will not just effect the AMD/SMD patients, also millions others with parkinson's diseases, alzheimer's diseases, ALS, spinal cord injuries, HIV etc. where they now see practical hope of treating the diseases with regenerative medicine.

4)If it is eventually come down to a ban in US, this will be bad for the US economies as companies will move off shore to "friendlier" countries to proceed and US will lost it edge as leading country in medical research and advancement. On top of that patients here will of course also gladly go off shore for the procedure done, probably way cheaper than what they would have to pay here. As of today, many patients already gone to China or India for some unproven stem cells procedures.

All these noises most likely are created and supported by religions extremists or groups, as they desperately wanted to get the attention of the world as they think this world is getting "sick" or "outrageous" from God's will. Ironically, most of them are medical scientists themselves, and try to persuade the public to use only adult stem cells. Here is a good example(see link). His organization probably one of the sponsors of the two adult stem cell scientists for the lawsuit that sue the government for federally funding the embryonic stem cell researches and wanted it banned. The problems is a lot of these extremists are very wealthy persons or organizations and as you know, in here, if you have money, you can make enough noises. Those two scientists themselves would not have enough money to put up with the legal fees, they are just the puppets.

http://www.frc.org/get.cfm?i=by04h12(This person, a doctor himself knew about the ACT's Blastomere patent but he chose to just ignore it).

This is the information about the lawsuits.

http://blogs.nature.com/news/201 ... case-try-again.html

http://www.bakerinstitute.org/pu ... Report50-111411.pdf

To me both adult and embryonic stem cells are valuable for medical research. They have pros and cons and needed one another to compare and contrast to get the best of both worlds. I can't see the political environment here will eventually ban embryonic stem cell research. If they do, I will move out of this country, as this country will be going backward and not much different than living in Afghan under Taliban. Look at the Personhood movement, it is going no where.

Regards,

IpohMan69

ACT is releasing 4th quarter and year-end results of 2011 tomorrow EOD March 1st. . There will be a conference call to discuss results on Friday, March 2nd at 9 am eastern time (10pm night time in Malaysia). I am more interested about some updates that probably going to be asked during the Q and A session. Thus I will try to tune in or do the replay. You can listen to the live stream via webcast online if you are interested, just need to register before hand(on the second link).

http://finance.yahoo.com/news/ad ... 2011-120500666.html

https://us.reg.meeting-stream.com/advancedcelltechnology030212/

Nachogy

We will find out more today regarding the stages of the research now, hopefully.

The financial report does not seem exciting for the last quarter.

IpohMan69

The company is asking for approval for reverse split( between 1 to 20 and 1 to 80) to be uplisting to NASDAQ board.

As you evidently seen now, the stock is taking a beating now because it does looks bad to current shareholders. But if you look deeper or if you did listen to the CC just now, there is good reasons behind it. I am busy today and I will write up more about it later. Bottom line is I will make money out of this, question is how much which also depends on how long do I hold the shares. Again, this is going to be long term investment.