2001諾貝爾得獎人-Professor Leland Hartwell講座

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Free and All Welcome!
You and your colleagues, friends, and students are cordially invited to a Public
Lecture on﹕

“Cancer Cure: Concepts and Advancements”


by Nobel Laureate Professor Leland Hartwell﹐
Nobel Prize in Physiology or Medicine (2001)

on 14th September 2004 (Tuesday), 8.00 pm

at Teratai Lecture Hall, Faculty of Science Lecture Hall Complex,University of Malaya

  

Program
Tuesday, 14th September 2004
8.00 pm                      Arrival of Guests and Light Refreshments
8.30 pm                      Speech by
                             President, Academy of Science Malaysia
                             Vice-Chancellor, University of Malaya
                             President, Malaysian Oncological Society

8.35 pm                      Introduction by Chairperson

8.40 pm                      Public Lecture by
                              Nobel Laureate Professor Leland Hartwell
                             “Cancer Cure: Concepts and Advancements”

9.40 pm                      Question & Answer

10.00 pm                      End of Programme


For further information and confirmation of attendance, please contact:

Ms Nitia or Ms Adzura
Academy of Sciences Malaysia
902-4, Jalan Tun Ismail, 50480 Kuala Lumpur
Tel: 603-2694 9898        Fax: 603-2694 5858
E-mail; nitia@akademisains.gov.my

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Prof. Leland Hartwell, Nobel Laureate






A co-recipient of the 2001 Nobel Prize in Physiology or Medicine
•  President and director, Fred Hutchinson Cancer Research Center, Seattle
•  Professor of genome sciences and Adjunct Professor of medicine, University of Washington School of Medicine, Seattle
•  American Cancer Society Research Professor of Genetics

Dr. Leland or Lee Hartwell has been studying the yeast cell for more than 35 years. Using the budding yeast that is essential for brewing beer and baking bread, Hartwell identified many genes that control cell division. Yeast presented many advantages for this work, including its rapid division time, its facile genetic system and its budding shape.

The genes that control cell division in yeast subsequently have been found also to control cell division in humans and often to be the site of alteration in cancer. In addition to displaying alterations in cell division, cancer cells, unlike normal cells, also are unstable genetically.

Hartwell also turned to yeast to investigate the basis for accurate cellular reproduction and discovered a new class of gene: "checkpoint" genes. These genes notice when mistakes have been made during cellular reproduction and halt cell division so that repair can take place.

Hartwell was born Oct. 30, 1939, in Los Angeles. In 1961 he earned a B.S. at the California Institute of Technology and in 1964 earned a Ph.D. from the Massachusetts Institute of Technology under the mentorship of Dr. Boris Magasanik. He conducted his postdoctoral work at the Salk Institute for Biological Studies from 1964 through 1965 with Dr. Renato Dulbecco. Hartwell was an assistant professor at the University of California, Irvine, from 1965-1968. He joined the University of Washington faculty in 1968 and has been a professor of genome sciences there since 1973.
In 1996 he joined the faculty of Seattle's Fred Hutchinson Cancer Research Center and in 1997 became its president and director.

Hartwell is the recipient of many national and international scientific awards, including the 2001 Nobel Prize in physiology or medicine. Other honors include the Albert Lasker Basic Medical Research Award, the Gairdner Foundation International Award and the Alfred P. Sloan Award in cancer research. He is a member of the National Academy of Sciences.

Hartwell lives in Seattle with his wife, Theresa Naujack.

Relevant websites:
http://www.nobel.se/medicine/laureates/2001/
http://www.nobel.se/medicine/laureates/2001/press.html
http://www.nobel.se/medicine/laureates/2001/hartwell-autobio.html

[ Last edited by yaoxin on 7-9-2004 at 01:17 PM ]

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二零零一年诺贝尔医学奖

瑞典诺贝尔奖委员会最近宣布，二零零一年的诺贝尔医学奖是由一位美国科学家和两位英国科学家获得，以表扬他们研究细胞调节周期的机制，所取得的突破，帮助科学家了解癌细胞出现的过程，对开发新的癌症治疗方法，有很大的帮助。

二零零一年的诺贝尔医学奖(Nobel Prize in Medicine)是由美国华盛顿大学(University of Washington)的哈特韦尔教授(Professor Leland Hartwell)、英国皇家癌症研究基金(Imperial Cancer Research Fund)的纳斯爵士(Sir Paul Nurse)及亨特博士(Dr. Timothy Hunt)获得，他们多年来，研究细胞(cell)成长的过程，发现重要的分子(molecules)，可以调节细胞分裂(division)及生长的机制，对了解因为染色体(chromosomes)的缺陷，而生产癌细胞(cancer cells)，有很大的帮助。

科学家指出，所有生物组织都是由细胞组成，而细胞的生长是通过细胞分裂；人类大约有一百万亿个细胞，都是从一个细胞分裂出来的，而人类在成长过程中，很多新的细胞从细胞分裂中产生，代替死去的细胞。

当一个细胞生长时，它会变大，然后复制它的染色体，变成两个，再将染色体分配到细胞分裂后所产生的两个细胞；这个细胞分裂过程，在哺乳动物(mammals)内，一般是需要十至三十小时，图中所见，是科学家解释细胞分裂的过程。